Benefits of Tadalafil
Can I get Tadalafil Online?
What is Tadalafil
Tadalafil is Generic Cialis
Tadalafil is a phosphodiesterase (PDE) class 5 inhibitor. Medications in this class are used to treat erectile dysfunction, pulmonary artery hypertension, benign prostatic hypertrophy (BPH), or the concurrent treatment of erectile dysfunction and BPH.
Tadalafil (generic for Cialis) is a lower-cost option for Cialis that contains the same active ingredients. It works exactly the same way as the brand-name medication in your body. In contrast to other oral ED medications, tadalafil provides two convenient treatment dosing options: once daily and as needed.
How Does Tadalafil Work
Blood Flow is Essential to Get and Maintain an Erection
An erection is the result of increased blood flow into the penis. Sexual stimulation increases blood flow into the penis, temporarily trapping it in spaces called the corpus cavernosum. These spaces make up most of the penis and surround the urethra, the tube shared by both the urinary and the reproductive systems.
Smooth muscle lines the small blood vessels called capillaries that enter the penis, contracting and relaxing to decrease or increase blood flow through them. Damage to these blood vessels from diabetes, high blood pressure, or lipid deposits can reduce blood flow.
When blood enters the penis and fills the corpus cavernosum, the swollen tissue presses on blood vessels draining the penis. This process results in vasocongestion or holding blood in the penis. The pressure within the penis increases, and it becomes rigid.
Tadalafil Promotes Blood Flow Into the Penis
Nitric oxide is a small molecule found throughout the body. It is released from nerve endings near the blood vessels in the corpus cavernosum of the penis after sexual stimulation. Nitric oxide triggers a chemical cascade that dilates blood vessels and increases blood flow into the penis, resulting in an erection. cGMP (another chemical in the cascade) levels must remain high to maintain the erection. Phosphodiesterase inactivates cGMP. When cGMP is deactivated, the smooth muscles in the walls of small blood vessels contract, reducing blood flow and ending the erection.
Oral ED medications, such as tadalafil, are phosphodiesterase inhibitors. By inhibiting phosphodiesterase, nitric oxide continues to trigger the cascade, and blood flow into the penis is maintained, meaning a firm erection. Understanding this cascade led to the development and subsequent FDA approval of tadalafil in 2003.
Frequently Asked Questions
Tadalafil is used to treat erectile dysfunction. It is a phosphodiesterase 5 (PDE5) inhibitor which means that it increases nitric oxide levels around blood vessels after sexual stimulation. Increased nitric oxide levels facilitate smooth muscle relaxation in the penis, allowing blood to fill the corpus cavernosa (hollow cavities) in the penis. This increases pressure in the penis, producing an erection.
Tadalafil is also used to treat benign prostatic hypertrophy and pulmonary artery hypertension.
Tadalafil can be prescribed as a daily dose or as needed.
If you are prescribed tadalafil as a daily dose, you take it once a day regardless of when or if you have sexual activity that day. Many men prefer this dose because the act of taking a medication is disconnected from sexual activity.
If you are prescribed tadalafil as needed, take the dose 30 to 60 minutes before planned sexual activity. Tadalafil may have an effect for up to 36 hours, but you need to be sexually aroused for it to work. The length of time it works is affected by food and alcohol consumption.
Tadalafil is not designed or licensed to increase the time to ejaculation or orgasm. However, some studies have suggested that it might delay ejaculation in some cases.
Tadalafil does not seem to consistently delay ejaculation and, therefore, should not be used for this purpose. Other medications are more effective in treating premature ejaculation.